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In contrast, Mel and GSH may have contributed to the prevention of apoptosis, possibly through inhibition of Cas-3, Cas-9, and Bax signaling pathways
doi: 10.1038/s42255-020-0254-1 207 HanXWangMDuanSFrancoPJKentyJHHedrickPet al
CTHRC1 in ovarian cancer promotes M2-like polarization of tumor-associated macrophages via regulation of the STAT6 signaling pathway
In conclusion, we revealed novel structurefunction relationships of glutaredoxins, gained insights regarding the enzymatic conversion of glutathione- and non-glutathione disulfide substrates, and identified two distinct substrate interaction sites that include a scaffold residue and the conserved dual activator Lys105 in ScGrx7 and Lys26 in PfGrx
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