Colvin KJ, Killen HS, Kanter MJ, et al
J Am Chem Soc 123:839850
That lets us consume less calories, but then also changes our body set point of where our weight is and can drop it down significantly. However, for some time, it was considered unfair to take the supply of GLP-1 drugs from people with diabetes - the original reason for the drug - and instead use it simply for weight loss, especially since it had not been tested for that
Tricyclic antidepressants including imipramine and amitriptyline are a mainstay of treatment for a variety of chronic pain states, although not FDA-approved for this indication (Tauben & Stacey, 2021)
No, patients should not commence GLP-1 receptor agonists solely for potential cognitive effects without medical consultation
Why this matters: Study comparing dieters with and without resistance training: those training lost 95% fat and 5% muscle