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Adipocyte-specific deficiency of Janus kinase (JAK) 2 in mice impairs lipolysis and increases body weight, and leads to insulin resistance with ageing
Growth hormone and its derivatives have maximum fat-burning effects when insulin is low and glucagon is elevated - which happens during fasting
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Tissue repair whether in tendons, gut mucosa, or skin is a gradual process that requires sustained peptide support over weeks rather than days
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