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However, there are studies indicating that under certain conditions insulin/IGF-1 signaling can provoke pro-inflammatory effects, e.g., through disturbing the Th17/Treg balance in autoimmune diseases [20]

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This fusion protein is capable of exerting the beneficial effects of GLP-1 on blood glucose regulation and insulin secretion while also targeting and inhibiting GIPR function through the antibody fragment

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10.1016/s0014-2999(97)01033-9 62 SikiricP.SeiwerthS.RucmanR.KolencD.VuleticL

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