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Cardiovascular (CV) damage in PASC CV complications are prevalent among PASC patients since ACE2 receptor-rich cardiomyocytes provide SARS-CoV-2 direct access to the heart

MECHANISM CATEGORIES RESEARCH CONDITIONS SAFETY Side effects Limited human safety data Animal toxicology shows wide therapeutic window Injection-site reactions reported anecdotally Known interactions Anticoagulants (theoretical, due to angiogenic activity unstudied) Contraindications Active malignancy (theoretical, due to angiogenic mechanism) Pregnancy/lactation (unstudied) REGULATORY STATUS FDA Placed on FDA Category 2 of the 503A bulks list (September 2023 update), barring compounding pharmacies from preparing it under section 503A

For patients who want to combine the two, the injection cadence is manageable

Cagrilintide can also be cycled on its own with periodic breaks

This translates into a broad safety profile fewer side effects like edema or insulin resistance than can occur with high-dose HGH therapy