Current therapeutic approaches and investigational drugs for NAFLD-related fibrosis primarily aim to reduce IR and correct metabolic abnormalities, thereby decreasing free fatty acid production, lipotoxicity, and excessive TGs accumulation in hepatocytes, mitochondrial dysfunction, and endoplasmic reticulum stress 123
After testing, use fortified foods and supplements when necessary
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Bonferroni-adjusted p -values are reported
doi:10.3390/biology10111165
The patients getting these treatments should be willing to sustain a lifestyle revolving around eating healthy and performing regular physical activity