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Under conditions of chronic energy flux constriction, compartment-specific regeneration efficiency may therefore become more relevant than bulk metabolite concentration
Research has also shown that NO exerts cytotoxic effects on respiratory epithelial cells and disrupts oxygen uptake by type II pneumocytes (93)
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Proinflammatory cytokines play a key role in astrocytic transformation, promoting increased APP expression, -site APP cleaving enzyme 1 activity and secreted A levels, all of which are linked to neurodegenerative disease pathology 90
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