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Tanou et al., 2012
Go natural
Avoid combining in the same application with strong acids (high-concentration AHA or BHA) because pH extremes can destabilize the copper complex
140,141 Although CSCs represent a functional cellular state, it has been demonstrated that their identification can be facilitated by utilizing specific cell markers such as CD133, CD44, EPCAM, and ALDH1, among others
Every compound with a handful of anecdotal reports and a social media following
If further testing continues to support the utility of these biomarkers to identify hepatotoxicity in other drugs besides acetaminophen in nonclinical species and in humans, the concept of biomarker qualification could be pursued for regulatory utility (US 2010)
