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Rare but serious side effects may include hypersensitivity reactions like rash and wheezing
doi: 10.1152/ajprenal.00532.2009 115
The bioactive compounds fabricate pro-inflammatory cytokines, like the interleukin-6 (IL-6) and tumour necrosis factor-alpha (TNF-alpha) which are active against the body inflammation (Wu et al
These GLP-1 receptor agonists help curb appetite by targeting hunger centers in the brain, enhance metabolic function by improving insulin sensitivity and slowing gastric emptying, and may even reduce the risk of developing type 2 diabetes by managing risk factors effectively
It may occur abruptly or over a longer duration and is accompanied by a burning sensation in the mouth
52 In a large meta-analysis by Chiang et al involving 106,395 participants and 55 RCTs, GLP-1 RA therapy was associated with an increased risk of gastroesophageal reflux disease (GERD) compared to placebo, with a reported relative risk of 2.19 (95% CI: 1.483.25)
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