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The ALT elevations were not associated with bilirubin elevations or AEs and thereafter steadily decreased without intervention or interruption of study drug

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297,298,299,301 Subsequent trials in patients with T2D and established HF showed that dapagliflozin and empagliflozin reduced the composite outcomes of worsening HF (defined as hospitalization for HF or an urgent visit for HF) or cardiovascular death by 2126%

IgE-mediated and T cell-mediated autoimmunity against manganese superoxide dismutase in atopic dermatitis