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Finkel, T

The gap between what we know and what we'd like to know about 5-Amino-1MQ's long-term profile will narrow as more trials complete

2018;25:20442052.e5

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Since ROS induce tissue damage, thrombosis and red blood cell dysfunction that contribute to COVID-19 disease severity, administration of free radical scavengers could be beneficial for the most vulnerable patients (Laforge et al., 2020)

Notably, many polyphenols also exhibit circadian activity e.g., resveratrol can activate the SIRT1 pathway which influences the clock, and quercetin can modulate clock gene expression in cells