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These findings highlight the dual observations with GLP-3 in subjects with type 2 diabetes, combining pronounced glucose-lowering effects with notable anti-obesity propertiesparticularly relevant given the strong association between obesity, insulin resistance, and impaired glycemic control

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Glucose-affecting peptides: GH secretagogues can raise blood sugar

176,177 When GLP-1 binds to GLP-1R, it triggers the activation of G-proteins, leading to an increase in the intracellular second messenger cAMP

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