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Mechanism of Action: A Multimodal Cellular Signaling Profile One of the most distinctive features of BPC-157 from a pharmacological research perspective is the absence of a single, well-characterized primary receptor target
What the mechanism does NOT prove: A mechanism observed in vitro or in rodents does not predict the magnitude, durability, or route-dependence of clinical benefit in humans
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S.MafongelliE.MannocciA.et al (2014)
Proposed mechanisms of MOTS-c: Activates AMPK Improves insulin sensitivity Enhances glucose utilization Increases metabolic flexibility Improves mitochondrial efficiency Supports exercise performance Why AMPK matters: AMPK is often called the body's metabolic master switch
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