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B420 is the probiotic strain in the formula, and the published 6-month RCT in 225 overweight and obese adults reported a body fat mass difference of -4.0% versus placebo (P=0.002), a 2.4 cm waist circumference reduction more than placebo, and a daily energy intake reduction of approximately 300 kcal compared to placebo (post-hoc factorial analysis).[9] The trial did not select for GLP-1 users, did not measure constipation as an endpoint, and the available evidence is at the ingredient-level human evidence tier

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(152) examined the correlation between bone loss during spaceflight and gut microbiome, as well as specific host metabolites

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A recent study from British Columbia, Canada, explored the effects of GLP-1 receptor agonists in nearly 11,000 patients with both autoimmune conditions and diabetes

Most women experience peak sexual desire around ovulation, when estrogen is highest