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Then a new question inevitably appears
The number on the scale is not the only endpoint
The risk is not established at the doses and durations used in clinical peptide protocols, but the theoretical basis for the concern is real and should not be minimized
Exogenously administered GSH protects against oxidative damage in cultured human RPE 17 , while GSH depletion was shown to cause cell death 18
Any papers resulting from these two trials do not appear to be indexed in major global databases like PubMed, and its not clear if they were ever published in peer-reviewed journals
Given the potential for reduced dietary intake and the mechanistic similarities retatrutide shares with approved GLP-1 medicines, a structured approach to nutritional monitoring is clinically sensible for patients receiving this treatment
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