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Eur J Radiol 46(2):115122
[5] [17] Many individuals taking Mounjaro for type 2 diabetes may consider magnesium supplementation for various reasons, including: Addressing documented magnesium deficiency Managing muscle cramps or fatigue Supporting general health and wellbeing Attempting to alleviate constipation, which can occur with Mounjaro If you are taking Mounjaro and considering magnesium citrate supplementation (rather than laxative use), the combination is generally considered safe at standard supplemental doses
Protein binding has little effect on the clearance of high-extraction drugs, as the liver's high metabolic capacity can efficiently remove the drug from binding proteins as it passes through