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Orexigenic (AgRP/NPY) & anorexigenic (POMC/CART) neurons integrate these signals, regulating food intake via Y1/Y5 & Mc4 receptors.

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surmount-1 tirzepatide weight loss non-diabetic trial obesity without diabetes non- diabetic once weekly for the treatment of in people with type 2 (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 SURMOUNT-1: Tirzepatide Drastically Comparison of Clinical Efficacy and

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surmount-1 tirzepatide weight loss non-diabetic trial obesity without diabetes non- diabetic once weekly for the treatment of in people with type 2 (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 SURMOUNT-1: Tirzepatide Drastically Comparison of Clinical Efficacy and
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