Improved insulin sensitivity : Particularly in women with PCOS, GLP-1 drugs can rebalance cycles by improving insulin resistance
Full model: Adjusted for sex, age, inclusion date, diabetes duration, Charlson Comorbidity Index, any diabetic complications, previous falls, inflammatory bowel disease, ever insulin use, ever glucocorticoid use, hypertension, kidney disease, alcohol, smoking and obesity, and stratified by osteoporosis
Energy improvements : Morning fatigue often lifts, and the afternoon crash many PCOS patients struggle with diminishes
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Most users who report positive changes describe a gradual onset over 2 to 6 weeks