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Pathogenic models of psoriasis emphasise the pivotal role of the IL-23/Th17 axis and blocking this axis might determine positive effects on psoriasis comorbidities

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Ganju and colleagues concluded, These results provide the first large-scale evidence supporting GLP-1RAs as a safe and potentially beneficial adjunct in Crohns disease management. They went on to note that prospective studies and guideline development are urgently needed to define their role in integrated IBD and metabolic care.

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