Chromodomain Y-like (CDYL) can act as a hydrolase for crotonyl-CoA, inhibiting the crotonylation modification of proteins like RPA1 [40]
Hence, physiological levels of ROS actively participate in cell cycle regulation, while increased or sustained levels rather lead to mutagenesis, inhibition of apoptosis and accelerated cell proliferation, causing cancer
M.GleasonC
453 Novel agents, including antibodies, ADCs, DDR inhibitors, epigenetic therapies, PROTACs, and nanomedicine delivery platforms, offer new opportunities for resistance-targeting interventions
Met loopbaan- en talentontwikkeling helpen we je kwaliteiten zichtbaar te maken en nieuwe ontwikkelrichtingen te ontdekken
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