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It is the simultaneous drift of dozens of biological systems away from their optimal states over decades

Tingling or Numbness (Paresthesia): Changes in GH and IGF-1 can occasionally lead to a sensation of tingling, often in the hands or feet

The brains phosphatidylserine content appears to diminish with aging, 179 and several clinical trials in older adults with self-reported memory concerns have found phosphatidylserine supplementation, at 300 mg per day, can improve memory and other aspects of cognitive function

Kraus et al

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No, shortness of breath is not listed as a common or characteristic side effect in FDA prescribing information for GLP-1 medications