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The buildup of misfolded or damaged proteins, such as amyloid- in AD and -synuclein in PD, occurs due to the failure of these pathways, causing cellular stress, inflammation, and neurodegeneration

This reduces upfront spend and frees resources for strategic investments in drug development, market access, and partnerships

Diverticulitis occurs when diverticulasmall pouches that can form in weakened areas of the colon wallbecome inflamed or infected

The key inclusion and exclusion criteria, including the list of prohibited medications, are presented in Table 1

For example, while AUD chronically increases the risk of diabetes, acute alcohol intoxication (even in absence of AUD) may cause hypoglycemia

Presented for research literature review only Macas M et al