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Whilst there is no established direct link between GLP-1 therapy and magnesium deficiency, selecting an appropriate supplement formparticularly one that minimises digestive discomfortcan support overall metabolic health

Exercise, fasting and other beneficial stressors like sauna therapy may increase IGF-1

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L-Carnitine is known to enhance athletic performance by improving muscle endurance, reducing muscle damage, and increasing blood flow to muscles

However, Novo Nordisk, Ozempics manufacturer, released results from two clinical trials in November 2025 that showed that taking an oral GLP-1 didnt slow disease progression among people with Alzheimers compared to those who took a placebo

The individual actions of GLP-1R and GIPR activation are difficult to separate out