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FASEB J 27 , 24512457 (2013)
Psoriasis affects the skin
Third, pluripotency TFs in various stem/progenitor cells fluctuate in their transcription (Chambers et al., 2007
Dihexa = powerful but unknown long-term safety
Research indicates preferential accumulation in actively dividing cells and tissues with high metabolic activity, including dermal fibroblasts, keratinocytes, and endothelial cells
This stability may explain why relatively low doses produce noticeable effects
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