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The National Association of Boards of Pharmacys May 2025 survey shows that compliant practices face no regulatory challenges (National Association of Boards of Pharmacy, 2025)
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Effective doses spanned six orders of magnitude (10 pg/kg to 10 mcg/kg)
The degree of deficiency correlated with both the severity and age of onset of the disease [93]
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Extended protocols beyond typical 8-12 week durations appear safe based on available evidence
PMCID: PMC12673431
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