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According to Eli Lilly, participants in Mounjaro clinical trials lost 12 to 25 pounds, with a reported 21.1% weight loss after 12 weeks and a total mean weight loss of 26.6% over 84 weeks
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This observation likely reflects that MIA-induced OA primarily targets cartilage, whereas changes of the subchondral bone occur secondarily and can be influenced by factors such as mechanical loading, individual variability, and baseline bone status 52
May 2011;96(5):E782-792
Janik, M
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