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Its value is in identifying functional pathway abnormalities that may deserve further investigation or nutritional support
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[5] Jensen TM, et al
Activation of Caspase-8 promotes Caspase-3-mediated apoptosis (Legembre et al., 2002), while inhibiting the RIPK1/RIPK3 axis (necroptosis) (Newton and Manning, 2016) and the NLRP3/Caspase-1 axis (pyroptosis) (Frank and Vince, 2019)
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