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In these studies, high-dose niacin treatment restored NAD + levels and provided functional benefits in adult patients: remarkable decrease of liver fat, increase of mitochondrial respiration and biogenesis, muscle strength and exercise tolerance 15
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In addition, it reverses intracellular acidosis (such as that in renal tubule acidosis), apparently by competing with diphosphopyridine nucleotide as a hydrogen receptor
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PMID 16443160
Cell membranes and liposomes dissociate C-reactive protein (CRP) to form a new, biologically active structural intermediate mCRPm
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