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Argireline (acetyl hexapeptide-3) : Marketed for wrinkle reduction via a different mechanism (reducing facial muscle contraction)
In general, studies included a low to moderate number of participants, but were either not controlled for confounding or were controlled only for age, rarely for other important variables
This can be an advantage for those seeking a gentler introduction to peptide therapy or with sensitivities to injections
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In recent years, the FDA has cracked down heavily on the compounding of these peptides