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Retatrutide has the highest overall adverse event burden, primarily because of the dysesthesia issue
Acetyl-coA and acetylcholine metabolism in nerve terminal compartment of thiamine deficient rat brain
Hrabetova S, Sacktor TC (1996)
If you suspect Ozempic may be contributing to erectile dysfunction, you can report this as a potential side effect through the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk)
It can even help with weight loss
This is since it exhibits a stronger affinity for the IGF receptor and lower affinity towards other proteins that may inactivate it
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