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Nature medicine , 28 (10), 2083-2091

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Review source type and study model

DNA fragmentation is a major cause of male infertility, as it compromises the integrity of the paternal genome, leading to poor fertilization outcomes and an increased risk of genetic abnormalities in the offspring

4-(pyridin-2-yldiazenyl)phenol (200 mg, 1 mmol) was dissolved in a mixture of DMF (10 mL), potassium carbonate (207 mg, 1.5 mmol), and potassium iodide(183 mg, 1.1 mmol)

Problemas tcnicos: La conservacin inadecuada del medicamento (debe refrigerarse y puede mantenerse a temperatura ambiente solo por el tiempo especificado en la etiqueta) o errores en la tcnica de inyeccin pueden comprometer la eficacia