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In addition, peptide therapy in general may lead to side effects related to the route of administration, which, in the case of ipamorelin, is subcutaneous injection

The reason liposuction is so popular is that it is safe and effectively removes fat from where it is not wanted and leaves fat alone where it is wanted

On April 22, 2026, the FDA removed 12 peptide substances from Category 2 of its 503A bulk drug substances list

10.1054/npep.1999.0017 76

Diabetes Care (2016) 39:15019

That matters because repeated injections in the same spot can cause lipohypertrophy, a thickened or lumpy area under the skin that may alter absorption