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Liraglutide is FDA approved for type II diabetes as well as for obesity and appears effective for AIWG: A study of patients (n = 97) taking clozapine or olanzapine who were randomized to add-on treatment with either liraglutide (1.21.8 mg daily) or placebo found that those in the liraglutide group lost an average of 4.7 kg compared to a gain of 0.5 kg in the placebo group (Larsen JR et al, JAMA Psychiatry 2017;74(7):719728)
They were at a lower risk of death, hospitalizations, and liver and gallbladder problems
Thats the standard clinical starting dose used in the SUSTAIN trials and prescribed on the label
The difference is in how they work
The vascular benefits of GLP-1 use might explain any improvements
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