Detection was performed on a quadrupole mass spectrometer operated in positive ion mode
The drug follows linear and predictable kinetics
Disclosures The authors have no personal, financial, or institutional interest in any of the drugs, materials, or devices described in this article
El-Hafidi M, Franco M, Ramrez AR, Sosa JS, Flores JAP, Acosta OL et al
This process may help support fat burning, endurance, and reduced muscle fatigue during exercise
Berberine is a plant alkaloid sold as an unregulated food supplement in the UK, not a licensed medicine approved by the MHRA It may enhance blood glucose-lowering effects of diabetes medications, increasing hypoglycaemia risk, particularly with insulin and sulphonylureas Potential interactions with anticoagulants (warfarin, DOACs) require specialist advice and may necessitate more frequent INR monitoring Berberine may increase blood levels of statins, immunosuppressants, and other CYP3A4-metabolised drugs, raising toxicity risks Always consult your GP before starting berberine if taking any prescription medications, pregnant, breastfeeding, or have liver or kidney disease Stop berberine at least 2 weeks before planned surgery and report any suspected side effects via the MHRA Yellow Card Scheme Table of Contents What Is Berberine and How Does It Work