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While the molecular mechanisms by which experimental or surgical manipulation of the lens drives the rapid upregulation of pro-inflammatory cytokine expression in LECs are currently unclear, LECs do rapidly induce Erk phosphorylation when isolated from animals (61) and this pathway is known to directly trigger immediate early transcription factor expression in other tissues (206, 207)
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Naltrexone is widely available as an affordable generic, while newer GLP-1 and GIP medications can be more expensive and harder to get for non-approved uses
2009 Jan-Feb;32(1):66-71
Frequently Asked Questions Can I take my regular diabetes medications while starting semaglutide
Puskarich & Jones (2024)
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