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We also found that the metabolic phenotype of male DIO Per-Gipr KO mice was recapitulated in female DIO Per-Gipr KO mice, which, like male Per-Gipr KO mice, showed no difference in body weight, body composition, food intake, energy expenditure, locomotor activity or substrate utilization, but the females did have robust glucose intolerance with impaired glucose-induced insulin secretion, despite normal insulin tolerance and unchanged plasma levels of blood glucose, insulin, triglycerides and cholesterol (Extended Data Fig

Presented for research literature review only Summer KH et al

MTs in obesity, insulin resistance, and diabetic complications As we explained in the previous section, the link between obesity and diabetes was found in an insulin resistance factor called resistin, which inhibits adipocyte differentiation

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Oxidative stress in autism spectrum disorderCurrent progress of mechanisms and biomarkers

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