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Discontinuation rates due to adverse events were dose-dependent and were driven predominantly by gastrointestinal side effects

Although an increase in blood clots was reported, researchers did not investigate whether Ozempic caused any of the blood clots

Reported side effects include: Other side effects reported include reduced appetite (also a side effect of the drug), tiredness, and skin sensitivity

Severe deficiency has been linked to low birth weight, pre-term birth, and megaloblastic anemia

Directive 2001/83/EC and its implementing Directive (EU) 2017/1572 govern finished product manufacturing but create binding obligations on API suppliers that feed into those finished-product pipelines