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We investigated a panel of seven antibodies, from multiple origins (Supplementary Table 1) and of diverse variable chain sequences (Supplementary Table 2), fused to the peptide with either a short (GGSA) or a long ([G 4 S] 3 A) amino acid linker

Baseline lab investigations: HbA1c, thyroid function, liver enzymes, kidney function, and lipid profile

Retatrutide is an emerging triple-agonist drug that acts on GLP-1, GIP, and glucagon receptors, which may make it even more powerful for weight loss and metabolic health compared to semaglutide

Obesity Nearly all respondents cover GLP-1s for type 2 diabetes (T2D), versus only 39% who provide coverage for obesity

GLP-1 analogs were initially developed for type 2 diabetes mellitus, their efficacy against obesity was demonstrated, and they were used as anti-obesity drugs 30