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Zinc, an anti-inflammatory antioxidant, which is required for the biological activity of thymulin, reduced the secretion of IL-1 beta (IC(50) = 62 microM), TNF-alpha (IC(50) = 1000 microM), and, to a lesser extent, IL-6

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According to the results, the elimination half-life (t 1/2 ) of the prototype BPC157 was less than 30 min, and BPC157 showed linear pharmacokinetic characteristics in rats and beagles at all experimental doses

doi: 10.1111/dom.15360 41 ThennatiRBuradeVNatarajanMShahiPNagarajaRPanchalSet al