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Accordingly, alanine mutagenesis of TM7 residues influenced both GLP-1 and oxyntomodulin affinity, but there was a larger effect on oxyntomodulin, consistent with its stronger interactions, however, interestingly these residues were more important for GLP-1-mediated cAMP production (Supplementary Figs 9, 10)

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It plays a role in transporting fatty acids into the mitochondria, where they are used for energy

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O'Rourke EA, Balzer B, Barry CI, Frishberg DP