Thats because they affect nutrient absorption, whereby the immune system becomes weak
It is synthesized in L-cells located in the intestinal mucosa, -cells found in the pancreatic islet, and neurons residing in the nucleus of the solitary tract
10.1016/j.ejphar.2016.04.004 132 StaresinicM.PetrovicI.NovinscakT.JukicI.PevecD.SuknaicS.et al (2006)
Furthermore, heme can drive TNF-- and ROS-mediated necroptosis [225], heme oxygenase 1-dependent ferroptosis [226], and NLRP3 inflammasome-associated pyroptosis [227], which are highly proinflammatory RCDs
\Cardiometabolic Risk: Reduced blood pressure, triglycerides, and inflammatory markers
Meister A: Glutathione deficiency produced by inhibition of its synthesis, and its reversal