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PMID 20143256 Pfizer/Hospira
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Zhi W, Li K, Wang H, Lei M, Guo Y
To determine the solution structural model of the p53 TAD2 -FOXO4-DRI complex using NMR spectroscopy, we recorded several sets of NMR experiments on two types of complexes: 13 C, 15 N-labelled p53 TAD2 -FOXO4-DRI and 13 C, 15 N-labelled FOXO4-LRI D -p53 TAD2 (see methods)
Because levels are often quite low before a deficiency is recognized, it can take some time for serum concentrations to even out and symptoms to subside
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