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Insomnia was not among the most prominently reported adverse events in published phase 2 trial data, though gastrointestinal side effects such as nausea may indirectly disrupt sleep

These symptoms can include nausea, headaches, and fatigue

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Persistent fatigue combined with muscle weakness, difficulty concentrating, or mood changes warrants evaluation for thyroid dysfunction, anemia, or depression

Understanding Semaglutide and How It Works Before looking at the interaction, it is essential to understand the primary medication in this equation