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Soundararajan and Kim, 2018

302,303,304 MIF has at least two catalytic activities: tautomerase and oxidoreductase activities

The copper complex gives reconstituted GHK-Cu a characteristic blue tint, which serves as a visual indicator

Observational data suggest potential involvement in inflammatory modulation, mammalian wound-associated signaling, and processes related to bone and connective tissue repair observed in laboratory settings

Gut surgery, pancreatic insufficiency, small intestinal bacterial overgrowth (SIBO), parasite infections, and certain autoimmune disorders are considered additional risk factors

The role of mGlu receptor signalling in pain modulation was recently reviewed in detail [36]