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1 Irrespective of the specific urate-lowering therapy (ULT) selected, fundamental principles entail commencing treatment concurrently with prophylaxis and initiating with a conservative dosage, followed by systematic monitoring of serum uric acid levels and subsequent dose adjustment until the therapeutic target is attained

Dimensions: 8000 x 4500 px | 67.7 x 38.1 cm | 26.7 x 15 inches | 300dpi Date taken: 31 May 2024

Eur J Clin Invest 42:637648 Tian YF, He CT, Chen YT, Hsieh PS (2013) Lipoic acid suppresses portal endotoxemia-induced steatohepatitis and pancreatic inflammation in rats

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This step conjugates cysteine with glutamate, generating -glutamylcysteine