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Contact your healthcare provider immediately if you experience: Signs of dehydration, including decreased urination, dark urine, extreme thirst, dizziness, or lightheadedness Blood in stools or black, tarry stools Severe abdominal pain or cramping that doesn't resolve Fever above 101F (38.3C) accompanying diarrhea Unintentional weight loss beyond expected therapeutic effects Persistent nausea and vomiting preventing adequate fluid intake Symptoms of pancreatitis, including severe upper abdominal pain radiating to the back Signs of gallbladder disease, such as right upper quadrant pain, fever, or yellowing of skin/eyes Symptoms of kidney problems, including reduced urine output, swelling, or confusion These warning signs may indicate complications requiring urgent evaluation