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Optimal clinical management of children receiving the ketogenic diet: recommendations of the International Ketogenic Diet Study Group
P-rank scores show that SGLT-2 inhibitors were ranked first in reducing total death (84.0%) and GLP-1RA were ranked second (81.9%) (Additional file 1: Table S2)
NICE has published guidance on pharmacological interventions for weight management, including NICE guideline CG189 (Obesity: identification, assessment and management) and a technology appraisal supporting the use of semaglutide (Wegovy) for adults with a BMI of 35 kg/m or above (or 3034.9 kg/m in certain circumstances) alongside a specialist weight management service
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Because GLP-1 receptors are present in brain regions connected to this system, researchers are exploring whether GLP-1 medications could indirectly influence addictive behaviors
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