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If your appetite is low, focus on high-quality protein during your hungriest time of day

Am J Physiol (1998) 274:R239

Because the milligram amount is fixed, a lighter body gets more drug exposure per pound: roughly 22% more at 70 kg and about a third less at 120 kg, compared with a 90 kg reference. The dose still comes from response and tolerability, but a lighter person is running a hotter exposure at the same number on the vial

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If you experience any side effects of GLP-1 drugs to your skin, hair, and nails, you can get relief by communicating with your medical team and partnering with a board-certified dermatologist

These BMI thresholds are based on the populations studied during major Semaglutide clinical trials