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When these receptors are stimulated, they reduce the frequency and amplitude of antral contractionsthe muscular waves that normally grind food and push it through the pyloric sphincter into the duodenum

PMID: 39555826 | doi:10.1056/NEJMoa2410027

The studys co-primary endpoints are changes in HRQoL and the composite of cardiovascular death and HF events

Unlike traditional acid reflux, LPR symptoms tend to show up in the throat and voice box, often without the hallmark sign of heartburn

These are trial averages