glp-1 analogue semaglutide Top Agonists Balance Weight Loss Efficacy, Safety glp-1 analogue semaglutide The GLP-1

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Goodman 2025 measured rate-pressure product directly under GLP-1R + glucagon co-infusion: +793 mmHgbpm at 60 minutes (95% CI 4601127) versus +663 for the GLP-1 agonist alone and +526 for glucagon alone, with the rise driven by heart rate rather than systolic pressure: Goodman BJCP 2025

10.1007/s10549-018-4753-7 36 FraserJ